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D J McConkey Selected Research

Telomerase (Telomerase Reverse Transcriptase)

12/2000Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion.

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D J McConkey Research Topics

Disease

19Neoplasms (Cancer)
03/2011 - 01/2000
10Neoplasm Metastasis (Metastasis)
10/2001 - 01/2000
5Urinary Bladder Neoplasms (Bladder Cancer)
07/2009 - 07/2000
4Pancreatic Neoplasms (Pancreatic Cancer)
03/2011 - 01/2000
3Melanoma (Melanoma, Malignant)
09/2008 - 05/2000
3Transitional Cell Carcinoma
09/2001 - 07/2000
2Leukemia
03/2011 - 12/2004
2Prostatic Neoplasms (Prostate Cancer)
01/2010 - 07/2000
2Carcinoma (Carcinomatosis)
07/2009 - 08/2000
2Colonic Neoplasms (Colon Cancer)
04/2001 - 02/2001
2Lymphatic Metastasis
12/2000 - 07/2000
1Hematologic Neoplasms (Hematological Malignancy)
03/2011
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
03/2011
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2011
1Glioma (Gliomas)
03/2011
1Lymphoma (Lymphomas)
03/2011
1Waldenstrom Macroglobulinemia (Macroglobulinemia)
03/2011
1Multiple Myeloma
03/2011
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
12/2004
1Skin Diseases (Skin Disease)
05/2002
1Psoriasis (Pustulosis Palmaris et Plantaris)
05/2002
1Mesothelioma
11/2001
1Disease Progression
09/2001
1Nevus (Nevi)
12/2000
1Spontaneous Remission
12/2000
1Inflammation (Inflammations)
09/2000
1Pulmonary Fibrosis (Fibrosing Alveolitis)
09/2000
1Lung Injury
09/2000
1Colorectal Neoplasms (Colorectal Cancer)
08/2000
1Adenocarcinoma
07/2000
1Heart Diseases (Heart Disease)
07/2000

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
07/2009 - 02/2000
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2001 - 05/2000
3InterferonsIBA
07/2009 - 09/2001
2Histone Deacetylase InhibitorsIBA
03/2011 - 11/2001
2Proteasome Endopeptidase Complex (Proteasome)IBA
03/2011 - 01/2010
2Bortezomib (Velcade)FDA Link
03/2011 - 09/2001
2Proteasome InhibitorsIBA
03/2011 - 01/2010
2Conditioned Culture MediaIBA
07/2009 - 04/2001
2Biomarkers (Surrogate Marker)IBA
07/2009 - 10/2001
2CaspasesIBA
07/2009 - 01/2009
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2008 - 02/2001
2Interferon-alpha (Interferon Alfa)IBA
03/2007 - 09/2001
2Tyrosine Kinase InhibitorsIBA
10/2001 - 02/2001
2orantinib (SU6668)IBA
10/2001 - 02/2001
2Matrix Metalloproteinases (MMPs)IBA
09/2001 - 12/2000
2GemcitabineFDA Link
09/2001 - 05/2000
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
02/2001 - 12/2000
2Monoclonal AntibodiesIBA
12/2000 - 07/2000
2Cetuximab (Erbitux)FDA Link
12/2000 - 05/2000
2Interleukin-8 (Interleukin 8)IBA
12/2000 - 05/2000
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2000 - 07/2000
2ErbB Receptors (EGF Receptor)IBA
12/2000 - 05/2000
2Paclitaxel (Taxol)FDA LinkGeneric
12/2000 - 07/2000
2Transcription Factors (Transcription Factor)IBA
09/2000 - 05/2000
2ThapsigarginIBA
07/2000 - 05/2000
1Lenalidomide (CC 5013)FDA Link
03/2011
1marizomibIBA
03/2011
1Small Interfering RNA (siRNA)IBA
01/2010
1Protein AggregatesIBA
01/2010
1Keratin-18 (Keratin 18)IBA
07/2009
1Amino AcidsFDA Link
01/2009
1Retinoblastoma ProteinIBA
01/2009
1Imatinib Mesylate (Gleevec)FDA Link
09/2008
1Caspase 3 (Caspase-3)IBA
03/2007
1Death Domain ReceptorsIBA
03/2007
1Biological ProductsIBA
12/2004
1fludarabineIBA
12/2004
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2004
1Methoxsalen (Oxsoralen)FDA Link
05/2002
1Butyric Acid (Butanoic Acid)IBA
11/2001
1Methotrexate (Mexate)FDA LinkGeneric
09/2001
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2001
1Cisplatin (Platino)FDA LinkGeneric
09/2001
1ParaffinIBA
09/2001
1ATP dependent 26S protease (26S proteasome)IBA
09/2001
1Vinblastine (Vinblastine Sulfate)FDA Link
09/2001
1Cadherins (E-Cadherin)IBA
09/2001
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
09/2001
1Oxygen (Dioxygen)IBA
04/2001
1CausticsIBA
04/2001
1Growth Factor ReceptorsIBA
02/2001
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
02/2001
1DNA ProbesIBA
12/2000
1Telomerase (Telomerase Reverse Transcriptase)IBA
12/2000
1Bleomycin (Blenoxane)FDA LinkGeneric
09/2000
1Environmental Pollutants (Pollutants, Environmental)IBA
09/2000
1Messenger RNA (mRNA)IBA
09/2000
1Phosphates (Orthophosphate)IBA
08/2000
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
08/2000
1Digoxin (Digitek)FDA LinkGeneric
07/2000
1AndrogensIBA
07/2000
1Cardiac GlycosidesIBA
07/2000
1oleandrinIBA
07/2000

Therapy/Procedure

8Therapeutics
01/2010 - 01/2000
2Drug Therapy (Chemotherapy)
09/2001 - 09/2001
1Intravesical Administration
03/2007
1Cystectomy
09/2001
1Neoadjuvant Therapy
09/2001
1Radiotherapy
09/2000